The Formulation of The Most Complete Immune System Fuel Ever Created – 23Vitals

An In-Depth Look into the Formulation Behind 23VITALS

Intentional Science Inspired by Love

Nothing is more important than your health and that of your friends, families, and the people that matter most. As immune challenges arise, we all need to be prepared with practical solutions to defend our health.

Formulation Goals

✅   Make it the absolute best.

✅   Make it taste delicious.

✅   Make it easy to remember.

✅   Make it affordable for all.

✅   Make it with love.

Every decision required a collective YES through this filter, "Is this in the best interest of those we love most?"

Fueling Each Core Function of The Immune System

Most of us have been living with various forms of stress, knowingly and unknowingly. Taking this into serious consideration, alongside the fact that age isn't on our side when it comes to optimal immune function, we took a uniquely refreshing approach. One that we see as the future of human optimization and longevity.

Start thinking of your immune system as your body's military response to threats. Each part has a specific role to play in defending you.

✅  PREPARE: Identify Threats

✅  DEFEND: Once Threatened

✅  SUPPORT: Communicate Effectively

✅  RECOVER: Provide Foundational Support

We've divided our ingredients into four blends that support the four major components of your "Immuno-Military" so it can function optimally.

Fueling Optimization vs. "Boosting" or "Ramping Up" The Immune System

We found that this is where most products claiming "immunity" fall short --> The approach of simply "boosting" or "ramping up" is not the way.

It's time to start thinking of our immune system through the same lens you would when thinking about building muscle, improving endurance, or becoming more proficient at a specific skill.

We formulated 23VITALS™ to deliver "sophisticated information" in the form of an orchestrated symphony of naturally occurring "Immuno-Potentiating" bioactive compounds to help train/educate/remodel/rejuvenate the Immune System --> Influencing and regulating the Immune System at a fundamental level.

BEYOND just "supporting" or "boosting"... --> THINK OPTIMIZATION

23VITALS™ contains a uniquely curated formula. The four bioactive ingredient blends collectively provide the immune system with supercharged fuel sources --> to function aggressively to early challenges to neutralize any threats by activating the production of individual critical cells of the innate arm of the immune system.

While also providing the fuel sources to help create more "fertile soil" - creating a supercharged environment to improve communication between all parts. Alongside a coordinated congregation of T and B-cells culminating in the production of immunoglobulins (antibodies) that are "educated/trained/remodeled/rejuvenated" to recognize any threats, present or future, more efficiently.

Beyond "defense" & "protection from infection"

We address ALL critical pillars and components of a healthy immune system.

23 INGREDIENTS
4 IMMUNO-ACTIVE BLENDS

Our immune system has one critical purpose:

TO PROTECT & MAINTAIN US

It is not 'only' from foreign infectious agents and internal housekeeping for the maintenance of cells, tissues, and organs. These fresh immuno-warriors are continuously replaced, replenished, and regenerated.

From cells & tissues in the lungs and gut to the brain and nervous system to skin, cartilage, joints, and muscles, to heart and blood vessels, to your glands and metabolism!

We've scoured and interpreted the rich scientific literature on the treasure trove of critical, bioactive nat compounds that Optimize Comprehensive Immune Function!

VITAL INNATE IMMUNO-RESILIENCE BLEND

This clinically research-backed Innate Immuno-Resilient blend of 23Vitals focuses on priming & fortifying your innate immune system to work at optimal levels BEFORE immune challengers are present. This powerful blend is filled with superstar and patented ingredients at clinically studied, efficacious doses in order to properly deliver the tools necessary to train and optimize your innate immune system to be “resilient” and “anti-fragile.”

Primary Mission: Identify Threats

Key Ingredient Features: 

✅   Can help support a healthy immune response, especially to seasonally changing & challenging environments.

✅   Natural Killer (NK) cells arm the immune system for first line, immediate response to previously unknown immune challenges.

✅   Promotes key messengers between the innate and the adaptive arms of the immune systems.

✅   Encourages functional activity of NK cells to support the immune system.

✅   Helps provide "Immuno-Resilience": resilience against seasonal immune challenges.

✅   Can help support a healthy immune response, especially to seasonally changing & challenging environments.

Learn more about the ingredients that
fuel your FRONTLINE Immuno-Warriors

wellmune® (1,3-1,6 beta-glucan)

A trademarked, yeast cell wall-derived source of beta-glucans, and is one of the most well studied immune ingredients available, as the subject of over 12 human clinical trials shown to prime innate immune cells such as macrophages, Natural Killer (NK) cells and monocytes to elicit a stronger immune response. They contribute to the phenomenon known as “trained immunity” where innate immune cells are “taught” or "educated" to recognize specific foreign immune challengers from previous exposure.

ResistAID®

A patented, all-natural North American Larch tree extract with clinically proven benefits in humans for optimizing both the Innate & Adaptive arms of the immune response.

L-Lysine

An essential amino acid that can increase the levels of IgG anti-bodies, acid/base balance, and cellular protection which are key to fortifying, preparing and supporting your immune system.

Quercetin Dihydrate

A polyphenol flavonoid found in a variety of fruits and vegetables, such as apples, onions, garlic, ginger and tea known for its extensive antioxidant properties for maintaining immune and blood vessel health. Quercetin can work well alongside Vitamin C that helps to recycle any quercetin that has been oxidized, in addition to zinc, by potentially allowing improved cellular entry and utilization, both of which are also found in 23VITALS for stabilizing mast cell inflammatory responses, and respiratory health benefits.

Emodin (Polygonum cuspidatum std. 95% emodin)

An anthraquinone compound found in several plant species, including Aloe vera and other botanicals that have been used for cardiovascular and bone health in traditional Eastern health systems. Emodin has immuno stimulant, antioxidant, anti-inflammatory properties, increase lysozyme activity of innate immunity, and it may interact with ACE2 receptors found in respiratory, heart, kidney and intestinal tissues.

Piperine (Piper nigum seed black pepper extract)

The main bioactive in black pepper extract, and can dramatically increase the absorption & bioavailability of certain ingredients in this blend, such as emodin and quercetin.


VITAL ADAPTIVE IMMUNO-DEFEND MATRIX

The adaptive immuno-defend matrix is specifically designed with bioactive compounds that work with your immune system and enhance its ability to fight off foreign microorganisms, as a first line of defense with nutraceutical preparation and first line of defense. These all-natural ingredients have been studied and proven to initiate and signal your body's adaptive (high specificity, selectivity and memory) response and make it work better!

Primary Mission: Defend Once Threatened

KEY INGREDIENT FEATURES: 

✅   Anthocyanins and Ellagic acid from Elderberry posses targeted control of normal day-to-day immune function.

✅   23VITALS Immune Factors has bioactive peptide fractions, including Lactoferrin that influence multiple immune mechanisms from GI tract, microbiome, to Gut-Associated Lymphoid Tissue (where a large part of Immune System is located).

✅   BI-04® patented and demonstrated to support cytokine levels & T-helper cell populations to provide balanced upper respiratory nasal and throat health.

✅   Aloe extract appears to be a regulator for both Th1 and Th2 getting us far at the ready to respond.

✅   Astragalus is a powerhouse bioactive for immune resilience.

Learn more about the ingredients that
fuel your SPECIALIZED Immuno-Warriors

23Vitals Immune Factors™

(Colostrum enhanced with Lactoferrin, Proline-rich Peptides, Immunoglobulins and Sialic acid)

A trademarked form of bovine colostrum found in 23Vitals, which is packed with lactoferrin, PRPs, and other proteins to help the body’s adaptive and innate immune system prepare, defend and support a healthy heart, lung, gut, vascular and musculoskeletal organ systems and recover against seasonal challenges, as well as maintain a balanced, resilient immune response.

Bl-04® (Bifidobacterium lactis)

One of the healthy probiotic bacterial strains known as Bifidobacterium lactis which may help support immune and lung function via improving the ratio of beneficial-to-undesirable bacteria in your microbiome. Scientists have also made a connection between bacteria in your gut and bacteria in your lungs called the “gut-lung axis" known to support lung immunity, as well as an adaptive, healthy immune response.

Elderberry (Sambucus nigra 10:1 extract)

Has been called “Nature’s Immune Tonic,” because it has been used for centuries in traditional health systems to optimize the immune response. Elderberry has a longstanding reputation and legacy as an immuno-enhancing ingredient due to high content of bioflavonoids and anthocyanins, which increase key cytokines that boost & regulate communication with other white blood cells.

Astragalus (Astragalus membranaceous root std. 0.5% astragalosides)

Contains long-chain carbohydrate molecules, which have been shown to have immuno-modulating properties that help balance the actions of immune-stimulant cytokines to get a more nuanced application of both the “brake” and “gas” pedals to stimulate macrophage response, improve the function of adaptive immunity via T-cells and B cells, and activate innate immunity natural killer (NK) cells.

ACTIValoe® (Aloe vera inner leaf gel extract std. 10% acemannan)

A highly pure ingredient derived from the Aloe Vera plant, used by Ancient Greeks as a “panacea,” as it seemed to support the health of all major organ systems. There are hundreds of bioactive compounds in aloe vera, but the most researched for boosting immune response is acemannan, shown to stimulate white blood cell (WBC) activity, as well as gut and microbiome, which regulate adaptive immune responses.


ORGAN SYSTEM, BLOOD FLOW & CYTOKINE WELLNESS MATRIX

This whole-body, multi-organ wellness matrix helps address all the other systems in the body that communicate and “talk” to the immune system and beyond. These ingredients help sustain and fortify an already comprehensive formula to deliver the ultimate immune solution.

Primary Mission: Communicate Effectively

KEY INGREDIENT FEATURES: 

✅   Maintain a healthy cytokine (e.g., IL-6, TNF-a, NF-kB) whole body, systemic balance.

✅   2nd line of defense with NAC supporting both immune function and lung/pulmonary health.

✅   Betullinic acid also adds to immune function benefits.

✅   Schisandra is Immuno-regulatory for both systemic and cell-based immune function.

✅   VasoDrive-AP® to uniquely improve signaling across the RAAS (Renin-Agiotensin-ALdoseterone) to redulte ACE2 receptor enzyme complex.

✅   Multi-Organ system support for optimal health, resilience & vitality.

Learn more about the ingredients that
fuel your INTEL Immuno-Warriors

OptiMSM® (Methylsulfonylmethane)

The world’s purest, safest and most consistent form of methylsulfonylmethane (MSM), a highly bioavailable source of sulfur found in hundreds of enzymes in your body known as reduction-oxidation (redox) reactions that protect DNA, proteins and fatty acids that make up infrastructure of all cells for immune support and crosses over outside of immune health to provide resilience to physical exercise and mental stress.

VasoDrive-AP® (Milk protein derived Vasoactive Tripeptides)

An all-natural, combination of milk protein-derived lactotripeptides, which are small protein molecules that can aid in balancing ACE:ACE2 enzyme balance closely tied to a healthy Renin-Angiotensin System (RAS) for promoting vascular, pulmonary and cardio health by controlling vasoconstriction, inflammation, fibrosis, oxidative stress and diminished blood flow.

Birch outer bark (Betula alba extract std. 3% betulinic acid)

Has demonstrated strong immuno-modulatory effects in humans via stimulatory cytokines like TNF-alpha, while decreasing expression of Interleukin-2 and 6 (IL-2, IL-6). A balance of cytokine activity where there is not too strong, but also not too weak of an innate and adaptive immune stimulation is key for having an effective immune response.

N-acetylcysteine (NAC)

A highly bioavailable form of the amino acid cysteine, which is the main amino acid precursor to the tripeptide glutathione, as part of the body’s master antioxidant enzyme, glutathione peroxidase. NAC supports healthy mitochondrial function, cellular defense by neutralizing free radicals with human clinical studies showing healthy respiratory, liver function, improved levels of lymphocytes, NK cells activity and antibody responses.

Schisandra chinensis (std. 2% schisandrins)

Widely used in traditional Eastern medicine for several thousand years with research showing the positive effects of Schisandra on liver function, lipid peroxidation and, more recently immune function.


IMMUNO-VITAMINS & MINERALS FOUNDATIONAL BLEND

A strong and healthy immune system relies on essential vitamins and minerals to maintain proper functionality, white blood cell turnover, replication, cellular communication and signaling. This matrix includes some of the cornerstone vitamins/minerals that have been shown to fortify immune function, response and recovery.

Primary Mission: Provide Foundational Support

KEY INGREDIENT FEATURES: 

✅   Essential micronutrient, vitamin/mineral blend to promote a healthy immune system.

✅   >500% DV of Vitamin C, >600% DV of Vitamin D3, >130% DV of Zinc.

✅   Vitamin D3 is key for promoting lung cell health, macrophage immune cell responses and modulate cytokine gene expression to help keep cytokine levels healthy.

✅   Zinc is a trace element that is a cofactor in over 300 enzymes, many of which affect your immune system. Deficiencies in zinc can lead to 50% decrease in NK cell function, 40% decrease in lymphocyte function, 48% lowered mitogen response and 30% reduction in T helper cells and antibody response.

✅   Selenium is critical for proper function of macrophages, NK cells, lymphocytes, as well as protection against day-to-day oxidative stress.

✅   Copper is an essential metal necessary for hundreds of enzymatic and redox processes. Like zinc, copper is also critical for immune function, including cytokine response, antibody protein function and activity, macrophage

Learn more about the ingredients that
fuel your SUPPORT Immuno-Warriors

Vitamin D3 (cholecalciferol)

One of the most important immune-vitamins as a white blood cell mediator that helps regulate the macrophage response critical to innate immunity, while controlling cytokine expression when the immune system is challenged to help protect against an overactive and hyper-stimulated immune response. Additionally, vitamin D3 regulates ACE2 receptor function, respiratory health and epithelial cells that line the lungs, mucosa and gut going beyond immune health with side benefits by supporting bone, calcium absorption, respiratory and even mood health.

Zinc (Zinc picolinate)

A trace element that is a cofactor in over 300 enzymes that affect your immune system necessary for NK cell function,T-cell (lymphocyte) function and production and B-cell antibody responses.

Vitamin C (ascorbic acid)

Part of a family of quintessential, classic immune fortifying essential vitamins that is especially in high-demand by hardworking white blood cells during seasonal immune stressors. It works in conjunction with other immuno-vitamins and minerals in this matrix to neutralize foreign threats to your health and wellbeing.

Selenium (L-selenomethionine)

Status is critical for proper function of macrophages, NK cells, lymphocytes, as well as protection against oxidative stress—all of which are key to innate and adaptive arms of an optimized immune response.

Copper (copper gluconate)

An essential metal necessary for hundreds of enzymatic and redox processes, and like zinc, copper is also critical for immune function, including cytokine response, antibody protein function and activity, macrophage and NK cell response, and of course, protection from oxidative stress.

Vitamin A (retinyl palmitate)

An essential micronutrient for immunity, cellular differentiation, growth, reproduction and maintenance of epithelial surfaces that provide barrier Immune protection to the mucosa lining the eyes, mouth, throat, lungs and gut/intestinal tract.

Vitamin B12 (methylcobalamin)

A versatile B-complex vitamin that plays a key role in many different body systems including maintaining healthy DNA synthesis, cell membrane and protein function for immune, nervous system & whole body wellness.

Two Entrepreneurs and Three dads learned a thing or two about survival over the last 40+ years. We intentionally poured all of our love and years of mastery within our crafts into 23VITALS™, with the knowledge of how powerful co-creation is when the driving force is love. I truly believe the positive reviews about how 'it just makes me feel better" and the fact that our product tastes so dang good is because we envisioned every scoop, giving your immuno-warriors a big hug and words of encouragement.

Incorporate 23VITALS™ into your daily routine and you will recognize a difference in how you feel.

(THIS PRODUCT DID NOT EXIST)

In March of this year(2020), we searched for all the things anyone concerned about the immune system should be taking. We recognized many areas for improvement and solved for each:

Thoughtfulness. We found most products advertising 'immunity' without taking a more in-depth investigation into what was possible with immune system optimization to become even more resilient.

Transparency. We recognized a large gap in co-operative education around all of the different things one should be doing--proactively, to improve our immune system's internal environment.

Affordability. We identified value discrepancies in both individual ingredients and comprehensive product pricing.

Ease of use. A few months of consuming a counter full of different individual supplements was enough to know we were on the right path, coming up with an easy to remember, once a day fuel that tasted amazing.

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You will not find a more comprehensive solution for immune system health & optimization.
 
You definitely won't find one where the power of love was poured into every finite detail--knowing the powerful impact this has on all things.
Our Promise

We know our product is the best option from a dietary supplement perspective for Total Immune Vitality. If you come across something after you've purchased from us that you believe is "better," or a product that we should be aware of - with respect to claims or efficacy - please share it with us so we can take a look. We'll be happy to provide a comparative analysis. 

Our Commitment

Earning your trust is our #1 priority. If you're unhappy with the product, simply call or email, and one of our team members will do their best to make you happy and address any concern. No games. We created this product because we knew there had to be better way for us to be proactive about our immune system, at a lower cost than what we experienced buying dozens of items off Amazon every month. 

Our Mission

We're going to do everything we can to help be a positive, empowering voice for those who desire being proactive to bolster and prime their immune systems. We leveraged the best nutraceutical science has to offer with broad expertise in human physiology and biochemistry to optimize heath & human performance in daily life. No more fear. We want people to feel safe, courageous and ready for anything.