“Truly the BEST Immunity supplement money can buy…”

We didn’t take ONE shortcut.

EVERY ingredient choice is justified… and was chosen to provide a specific role - individually and collectively. 

Many brands are making strong claims based on “mega-dosing” vitamin C and zinc. 

We chose another route. We created a real solution. 

One Scoop. Once a Day. 

23Vitals™ was designed to promote the most complete, balanced, regulated and strong innate + adaptive immune response that is up for daily challenges, while tempering the blood cytokine profile, and also maintaining healthy blood flow, blood clotting balance, respiratory and microbiome/ gut health…making this ultimate immune solution a versatile and comprehensive ally for optimal immune function.

23Vitals™ is an orchestrated symphony of naturally occurring "Immune-Potentiating" bioactive ingredients to help train, remodel, rejuvenate and fortify the Immune System.

23Vitals™ has the sophistication to take all the guess work out of finding the right, clinically-supported nutraceutical immune product, because it can help regulate the immune system at a fundamental level. It goes beyond just "supporting," since the immune system is enormously dynamic, generating approximately 6 Million new immune cells every minute…daily. As a result,

23Vitals™ has a profound impact on immune function by contributing to rejuvenating and remodeling the immune system into a more effective and resilient one to empower consumers and their families.

23Vitals™ uses 4 different Immuno-Active ingredient blends organized with a sophisticated treasure trove of bioactive natural compounds to comprehensively prepare, defend & support your healthy immune system, and respond to environmental immune stressors. Put simply, 23Vitals™ can be used daily to optimize immune health and promote a balanced inflammatory response.

DIVE DEEPER into ALL 23 BIOACTIVE INGREDIENTS BELOW

VITAL Innate Immuno-Resilience Blend:

ResistAID® is a patented, all-natural North American Larch tree extract with clinically proven benefits in humans for optimizing both the Innate & Adaptive arms of the immune response. 

L-Lysine is an essential amino acid that can increase the levels of IgG anti-bodies, acid/base balance, and cellular protection which are key to fortifying, preparing and supporting your immune system.

Wellmune® (1,3-1,6 beta-glucan) is a trademarked, yeast cell wall-derived source of beta-glucans, and is one of the most well studied immune ingredients available, as the subject of over 12 human clinical trials shown to prime innate immune cells such as macrophages, Natural Killer (NK) cells and monocytes to elicit a stronger immune response. They contribute the phenomenon known as “trained immunity” where innate immune cells are “taught” or "educated" to recognize specific foreign immune challengers from previous exposure.

Quercetin Dihydrate is a polyphenol flavonoid found in a variety of fruits and vegetables, such as apples, onions, garlic, ginger and tea known for its extensive antioxidant properties for maintaining immune and blood vessel health. Quercetin can work well alongside Vitamin C that helps to recycle any quercetin that has been oxidized, in addition to zinc, by potentially allowing improved cellular entry and utilization, both of which are also found in 23Vitals™ for stabilizing mast cell inflammatory responses, and respiratory health benefits.

Emodin (Polygonum cuspidatum std. 95% emodin) is an anthraquinone compound found in several plant species, including Aloe vera and other botanicals that have been used for cardiovascular and bone health in traditional Eastern health systems. Emodin has immunostimulant, antioxidant, anti-inflammatory properties, increase lysozyme activity of innate immunity, and it may interact with ACE2 receptors found in respiratory, heart, kidney and intestinal tissues. 

Piperine (Piper nigum seed black pepper extract) is the main bioactive in black pepper extract, and can dramatically increase the absorption & bioavailability of certain ingredients in this blend, such as emodin and quercetin.

VITAL Adaptive Immuno-Defend Matrix:

23Vitals Immune Factors™ (Colostrum enhanced with Lactoferrin, Proline-rich Peptides, Immunoglobulins and Sialic acid) is a trademarked form of bovine colostrum found in 23Vitals™, which is packed with lactoferrin, PRPs, and other proteins to help the body’s adaptive and innate immune system prepare, defend and support a healthy heart, lung, gut, vascular and musculoskeletal organ systems and recover against seasonal challenges, as well as maintain a balanced, resilient immune response. 

Elderberry (Sambucus nigra 10:1 extract) has been called “Nature’s Immune Tonic,” because it has been used for centuries in traditional health systems to optimize the immune response. Elderberry has a longstanding reputation and legacy as an immuno-enhancing ingredient due to high content of bioflavonoids and anthocyanins, which increase key cytokines that boost & regulate communication with other white blood cells.

Astragalus (Astragalus membranaceous root std. 0.5% astragalosides) contains long-chain carbohydrate molecules, which have been shown to have immunomodulating properties that help balance the actions of immune-stimulant cytokines to get a more nuanced application of both the “brake” and “gas” pedals to stimulate macrophage response, improve the function of adaptive immunity via T-cells and B cells, and activate innate immunity natural killer (NK) cells.

ACTIValoe® (Aloe vera inner leaf gel extract std. 10% acemannan) is a highly pure ingredient derived from the Aloe Vera plant, used by Ancient Greeks as a “panacea,” as it seemed to support the health of all major organ systems. There are hundreds of bioactive compounds in aloe vera, but the most researched for boosting immune response is acemannan, shown to stimulate white blood cell (WBC) activity, as well as gut and microbiome, which regulate adaptive immune responses.

Bl-04® (Bifidobacterium lactis) is one of the healthy probiotic bacterial strains known as Bifidobacterium lactis which may help support immune and lung function via improving the ratio of beneficial-to-undesirable bacteria in your microbiome. Scientists have also made a connection between bacteria in your gut and bacteria in your lungs called the “gut-lung axis" known to support lung immunity, as well as an adaptive, healthy immune response.

Organ system, Blood flow, and Cytokine Wellness Matrix:

OptiMSM® (Methylsulfonylmethane) is the world’s purest, safest and most consistent form of methylsulfonylmethane (MSM), a highly bioavailable source of sulfur found in hundreds of enzymes in your body known as reduction-oxidation (redox) reactions that protect DNA, proteins and fatty acids that make up infrastructure of all cells for immune support and crosses over outside of immune health to provide resilience to physical exercise and mental stress.

N-acetylcysteine (NAC) is a highly bioavailable form of the amino acid cysteine, which is the main amino acid precursor to the tripeptide glutathione, as part of the body’s master antioxidant enzyme, glutathione peroxidase. NAC supports healthy mitochondrial function, cellular defense by neutralizing free radicals with human clinical studies showing healthy respiratory, liver function, improved levels of lymphocytes, NK cells activity and antibody responses.

VasoDrive-AP® (Milk protein derived Vasoactive Tripeptides) is an all-natural, combination of milk protein-derived lactotripeptides, which are small protein molecules that can aid in balancing ACE:ACE2 enzyme balance closely tied to a healthy Renin-Angiotensin System (RAS) for promoting vascular, pulmonary and cardio health by controlling vasoconstriction, inflammation, fibrosis, oxidative stress and diminished blood flow.

Schisandra chinensis (std. 2% schisandrins) has been widely used in traditional Eastern medicine for several thousand years with research showing the positive effects of Schisandra on liver function, lipid peroxidation and, more recently immune function.

Birch outer bark (Betula alba extract std. 3% betulinic acid) has demonstrated strong immunomodulatory effects in humans via stimulatory cytokines like TNF-alpha, while decreasing expression of Interleukin-2 and 6 (IL-2, IL-6). A balance of cytokine activity where there is not too strong, but also not too weak of an innate and adaptive immune stimulation is key for having an effective immune response.

Immuno-Vitamins & Mineral Foundation Matrix:

Vitamin A (retinyl palmitate) is an essential micronutrient for immunity, cellular differentiation, growth, reproduction and maintenance of epithelial surfaces that provide barrier Immune protection to the mucosa lining the eyes, mouth, throat, lungs and gut/intestinal tract.

Vitamin C (ascorbic acid) is part of a family of quintessential, classic immune fortifying essential vitamins that is especially in high-demand by hardworking white blood cells during seasonal immune stressors. It works in conjunction with other immuno-vitamins/minerals in this matrix to neutralize foreign threats to your health and wellbeing. 

Vitamin D3 (cholecalciferol) is one of the most important immune-vitamins as a white blood cell mediator that helps regulate the macrophage response critical to innate immunity, while controlling cytokine expression when the immune system is challenged to help protect against an overactive and hyper-stimulated immune response. Additionally, vitamin D3 regulates ACE2 receptor function, respiratory health and epithelial cells that line the lungs, mucosa and gut going  beyond immune health with side benefits by supporting bone, calcium absorption, respiratory and even mood health. 

Vitamin B12 (methylcobalamin) is a versatile B-complex vitamin that plays a key role in many different body systems including maintaining healthy DNA synthesis, cell membrane and protein function for immune, nervous system & whole body wellness.

Zinc (Zinc picolinate) is a trace element that is a cofactor in over 300 enzymes that affect your immune system necessary for NK cell function,T-cell (lymphocyte) function and production and B-cell antibody responses. 

Selenium (L-selenomethionine) status is critical for proper function of macrophages, NK cells, lymphocytes, as well as protection against oxidative stress—all of which are key to innate and adaptive arms of an optimized immune response.

Copper (copper gluconate) is an essential metal necessary for hundreds of enzymatic and redox processes, and like zinc, copper is also critical for immune function, including cytokine response, antibody protein function and activity, macrophage and NK cell response, and of course, protection from oxidative stress.

Well... that depends on what you like. Flavoring nutritional supplements has become as much of an art as there is science behind its development. 

Staying true to product intent and ensuring that each ingredient is able to shine is where 23 Vitals leaves the competition behind. Where most choose simply to leave “difficult to flavor” ingredients out, we chose to take them head on.

Spending an inordinate amount of time in R&D, we chose flavors that work well with the ingredient’s natural profiles, reducing the need for overdoing maskers and allowing the ingredients themselves to show through.

We chose not to remove some of vitamin and mineral notes, emphasizing their need to be in the formula, and instead, focused on pairing the bitter and stringent components with sour naturally occurring citrus fruits.

By doing this, we settled on two delicious flavors that inspire both youthfulness and energy through common, yet reminiscent thoughts of two of the most traditional and iconic, semi-sweet treats we all remember having while growing up.

Orange Creamsicle: 

This flavor was meant to evoke that summery classic treat; a nostalgic creme-filled orange popsicle. The flavor combines sweet dairy creamy notes with a zesty citrus, orange flavor at the start and finish. Aroma is also reminiscent of ripe, sweet Valencia oranges.

Strawberry Lemonade: 

This flavor has an upfront tart, sweet and lightly sour lemonade, balanced with notes of true-to-life ripe, sweet strawberry finish. It's as if a handful of sweet jumbo, red strawberries were muddled at the bottom of a freshly squeezed glass of ice-cold lemonade. Aroma is of a floral, ripe strawberry garden.